Archives — October 2026

In pooled phase 3 data, mepolizumab lowered mean yearly systemic corticosteroid exposure by 178.97 mg in patients with a BEC of ≥150 cells/µL. Mepolizumab (Nucala) reduced total yearly systemic corticosteroid (SCS) exposure, particularly high-dose courses, in patients with COPD and type 2 inflammation receiving inhaled triple therapy, according to pooled phase 3 data presented at the American College of Chest Physicians (CHEST) 2026 Annual Meeting in Phoenix.¹,²Although treatment guidelines recommend SCS for COPD exacerbations, these agents are associated with complications in this population, prompting interest in targeted therapies capable of limiting their use.¹ Mepolizumab, a humanized monoclonal antibody targeting interleukin-5 (IL-5), is approved for patients with COPD and an eosinophilic phenotype.

With Hollywood veterans Jan-Michael Vincent and Ernest Borgnine in the cockpit, Airwolf spectacular aerial action, and pure '80s escapism. The coolest helicopter ever defined this '80s TV classic

Given the serious nature of the Elden Ring game, it’s honestly pretty amazing that there’s not just one gag manga based on it, but now two comedies building on its established characters and lore. But here we are! Yen Press previously released single chapters of Elden Ring: Distant Tales Between from Haruichi in English, and now the first full volume is out and explores moments in the lives of Roderika, Brother Corhyn, Rya, and Blackguard Big Boggart. It’s less joke-after-joke than Elden Ring: The Road to the Erdtree, while still offering a similar sort of tone. Recommended Videos Editor’s Note: There will be no spoilers for the character stories found in the first volume of the Elden Ring: Distant Tales Between manga below. While the Elden Ring: Road to the Erdtree manga follows a specific Tarnished named Aseo, the Distant Tales Between dedicates each chapter to a major NPC we may or may not meet as we play. It reads more as a short story collection. Which is beneficial, in its way. I think it might be more appealing to someone coming from the game as a result of the decision, since it could be highlighting someone you connected with when playing through your Tarnished’s story.

Air Canada, WestJetWS FilesPublished on:18 Oct 2026, 7:00 pmLoading content, please wait... CdnpoliCanadian Transportation AgencyCanadian Automobile AssociationBill C-31

Losing your train of thought or searching for a familiar word can raise some serious concerns for women approaching menopause. Researchers at Toronto Metropolitan University are working on investigating how this transition affects memory and how these changes impact brain health later in life. On this Menopause Day, Natasha Rajah, a professor of Psychology and Tier 1 Canada Research Chair in Sex, Gender and Diversity in Brain Health, Memory and Aging at TMU, is highlighting the research examining menopause and memory related issues showing signs of early dementia.

Grace, 26, says working in a startup is ‘a grind’ but it’s easier to advance her career at a smaller company

We present a case of a six-month-old female with a five-month history of right-sided torticollis that showed little improvement despite physical therapy. She presented to the emergency department due to parental concern for pneumonia, with congestion and cough without respiratory distress. Physical examination demonstrated leftward rotation and right lateral flexion of the head and cervical spine, consistent with the previously diagnosed right-sided torticollis. Chest radiographs were obtained in the workup for pneumonia and incidentally revealed segmentation anomalies of the cervical and upper thoracic spine as well as multiple bilateral bifid and fused ribs, more pronounced on the right. The radiographic findings were interpreted as highly suggestive of Klippel-Feil syndrome (KFS). In the setting of refractory torticollis and characteristic congenital vertebral abnormalities, the diagnosis of KFS was made. No acute complication requiring immediate intervention was documented. Referral to appropriate specialists was recommended for further evaluation and longitudinal management. This case highlights the importance of maintaining a broad differential diagnosis when evaluating refra

Waldenström macroglobulinemia (WM) is an indolent mature B-cell lymphoproliferative disorder defined by bone marrow infiltration by lymphoplasmacytic lymphoma (LPL) and an associated serum monoclonal immunoglobulin M (IgM) gammopathy. In this case report, we describe a patient presenting with two serious and rare IgM-mediated complications of WM that require urgent treatment: secondary cold agglutinin syndrome and hyperviscosity syndrome. With prompt diagnosis and therapeutic plasma exchange, the patient's IgM-mediated complications improved, with a marked reduction in serum IgM and resolution of hyperviscosity-related symptoms. This highlights the importance of recognizing the possible complications of an otherwise indolent disease.

AutomobilesAutomaker to revamp production processes to cut development times by 40%A prototype electric vehicle unveiled by Subaru. The company plans to save time on development by digitizing some processes. (Photo by Kantaro Fushiki)KANTARO FUSHIKIOctober 19, 2026 03:35 JSTTOKYO -- Subaru plans to introduce software-defined vehicles that can be updated over-the-air later this decade, the Japanese automaker said, while also increasing the use of digital design and testing to cut development time for next-generation cars by 40%.

Classic gems, tasteful customs, legendary supercars - for Silvian, they're all fair game. He's been in love with cars and motorcycles for as long as he can remember, so it made perfect sense to eventually turn that passion into a full-time writing career. Around six years and more than 3,000 articles later, he is still going strong and doesn't plan on hitting the brakes anytime soon. We all know China doesn’t take kindly to those pesky pop-out door handles, having mandated an all-out ban back in February. It will come into effect on January 1, 2027, and Chinese lawmakers at the Ministry of Industry and Information Technology (MIIT) aren’t planning to hang up the gloves just yet. As a matter of fact, the door handle saga might’ve been just the warm-up. MIIT’s crosshairs are now aimed at a trending feature we really wouldn’t mind seeing less of – annoyingly large touchscreens prone to distracting the driver. Quite frankly, we’re more than happy to cheer them on in this regard, and others may want to consider taking this particular page out of China’s rulebook.

As marijuana use becomes more common and legal in most U.S. states, patients who use cannabis may face a significantly higher risk of heart attack around the time of surgery, while also showing an unexpected lower risk of dangerous blood clots in the veins, suggests a study presented at the ANESTHESIOLOGY 2026 annual meeting.

GLP-1 medications, widely prescribed for diabetes and weight loss, may also help protect people from serious complications after surgery. People taking GLP-1 medications had lower rates of major heart-related complications and infections after surgery than those not taking the drugs, according to results of a study of more than 2 million adults undergoing surgery presented at the ANESTHESIOLOGY 2026 annual meeting.

Patrick Witt announced his departure from the White House last week.

With prices going up on, well, everything, having the ability to work on your own car (as long as the electronics allow for it) is a big money saver. There's a decent segment of individuals who can't do these things on their own, though, and it's possible, video games can help their journey to learn. Former Jalop Andrew Collins brought up the concept in 2020 with a video game called "Wrench," a grease-less automotive simulator that let you get your virtual hands dirty fixing cars in VR. A similar game released in 2021 called "Car Mechanic Simulator. " Now in 2026, "Wrench" has returned in a much more mature and updated version. YouTuber TalksWithNoise took to testing the concept in real time with a recent video, "I Tried Using a Video Game to Fix My Miata. "

(left to right: MPs Chris D'entremont, Matt Jeneroux, Michael Ma, Marilyn Gladu)House of CommonsPublished on: 18 Oct 2026, 6:19 pmLoading content, please wait...

Johnson joins CarBuzz on March 2026. He's currently studying MA Automotive Journalism at Coventry University in the UK which is the only course in the world to focus on this specific subject. He studied history in university which he combines the research and writing skills to produce contents related to automotive topics. Johnson’s passion for cars orginated from his early childhood which he grew up watching iconic Japanese anime Initial D and Pixar movie Cars and fell in love with all the stuff related to cars. According to Johnson’s family, he would be able to name the models and make of the vehicles on the road from a very young age.

Shaun Farrell FacebookPublished on: 18 Oct 2026, 6:14 pmLoading content, please wait...

De Niro's best gangster quote reveals the dark side of loyalty. Robert De Niro’s best gangster movie quote is a lesson in mob loyalty

Some quantum systems are so complex that even the most powerful supercomputers struggle to simulate their behavior. One solution is quantum simulation: building a controllable quantum system in the lab and tuning it to mimic the one researchers want to understand.

In optical fibers, chips and other light-guiding devices, minor defects can scatter photons and disrupt their path. A new study demonstrates a way to reveal properties which, in certain systems, help light wave behavior withstand such flaws. The method could help speed up the search for new kinds of electronics and optical technologies, and contribute to more reliable quantum devices.

Starlink satellites ready for deployment. WikipediaPublished on: 18 Oct 2026, 6:00 pmLoading content, please wait...

What happens when you bring researchers, clinicians, policymakers, innovators and people with lived cancer experience together in the same space? A lot of conversations, new connections, interesting projects… and apparently, some very fun photobooth pictures too!

In August 2019, Omar Rajeh sat in his bedroom, listening to the sound of pounding percussion with his world in crisis. In the midst of political instability, Citerne Beirut, a theatre and cultural centre Rajeh had founded in his native Lebanon, was forced to close, dismantled by order of the local government, who planned to build an incinerator on the site. Heartfelt … Omar Rajeh in Dance Is Not for Us. Photograph: Tristram Kenton/the GuardianRajeh tells us that as a teenager, coming of age at the end of the Lebanese civil war, dance had always seemed like the most revolutionary thing he could do. Now here he is, more than three decades later, still dancing – out of frustration, defiance, resistance and a desire to connect. As the percussive score gains momentum, Rajeh’s busy body builds up a sweat. In this danced stream of consciousness, Rajeh is not always an especially elegant mover, but he dances like it’s a necessary thing to do. Part of this year’s Dance Umbrella festival, Dance Is Not for Us is a solo that appears at times like an explosion of physical instinct, but it is mostly calm, considered musings on the nature of choreography, with all its workings exposed.