Simple medical card game reduces preoperative anxiety in children - News-Medical

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply. AbstractWhether documented preoperative statin exposure is associated with short-term mortality after aortic valve replacement (AVR) is uncertain. This retrospective multicohort study included 5,291 AVR records from SNUH, MIMIC-IV, and eICU. The primary analysis compared no documented versus any documented statin exposure for recorded 30-day mortality in SNUH and MIMIC-IV using overlap weighting and fixed-effect pooling. Exposure-window, recorded 365-day, IPTW, and SNUH available-follow-up analyses were sensitivity analyses; eICU and agent-specific analyses were exploratory. Overlap-weighted 30-day risks with versus without documented exposure were 1.29% versus 2.55% in SNUH and 1.18% versus 2.36% in MIMIC-IV; the pooled HR was 2.01 (95% CI, 0.98 to 4.11; P = 0.056). A 1-day MIMIC-IV window reclassified seven records and, pooled with the SNUH 24-h definition, yielded an HR of 2.29 (95% CI, 1.14 to 4.61; P = 0.

Staying active before surgery may do more than strengthen the body for recovery - it may protect the brain. Regular physical activity at least seven times a week before cancer surgery was linked to a lower risk of developing postoperative delirium, according to research presented at the ANESTHESIOLOGY® 2026 annual meeting. Postoperative delirium is a sudden state of confusion that affects about 20% of patients undergoing surgery. It is especially common in older adults and can affect attention, memory and thinking. It is also linked to longer hospital stays, delayed recovery and increased risk of death.

Featured topic and speakerChemotherapy can affect appetite, taste, smell and energy levels, making mealtimes challenging for both patients and caregivers. In this video, Nate Wood, MD, MHS, shares practical tips for supporting a loved one through cancer treatment with comfort, compassion and realistic expectations. Learn why eating can become difficult during chemotherapy, which gentle foods may be easier to tolerate, and how caregivers can offer support without adding pressure. Dr. Wood also discusses the importance of working with your physician, oncologist and dietitian to find personalized solutions during treatment. Remember: every person's experience with chemotherapy is different. Always follow the recommendations of your health care team regarding nutrition and treatment. Find out what doctors want patients to know about cancer screening and prevention. For more expert-backed fitness, health and wellness content, subscribe to our channel. Get the latest health news, trending topics, and public health information delivered to your inbox every week. Follow #AMA on social media.

Controversial vaccine researchers who have been praised by Robert F Kennedy Jr, the US Department of Health and Human Services (HHS) secretary, had their offices in Guinea-Bissau raided by judicial police, who seized doses of hepatitis B vaccines, officials said on Facebook. The researchers have been at the heart of an ongoing dispute over research on African newborns, supported by $1.6m from the US Centers for Disease Control and Prevention (CDC) and matched by the Pershing Square Foundation and the Bluebell Foundation for a total of $3.2m. The police search took place on Monday, involving “investigative procedures aimed at clarifying the circumstances related to the said batch of vaccines”, according to the social media post, which was translated from Portuguese. The announcement noted that seizing the immunizations did not point to “irregularities in the quality, safety, or effectiveness of the vaccines”. The Bandim Health Project recently posted a letter of approval for the trial from Guinea-Bissau’s national ethics committee at the ministry of public health, dated 14 July and signed by the committee’s president, Mouhammed Djicó Ould Ahmed.

Reducing damage to the nuclei of heart muscle cells improved heart function and dramatically extended survival in mice with a form of inherited heart disease, according to a new study led by Cornell researchers. The findings point to new approaches for understanding and potentially treating LMNA-related dilated cardiomyopathy, a disease that leads to heart failure and sudden cardiac death. The study, published in Circulation Research, was directed by Jan Lammerding, a professor in the Meinig School of Biomedical Engineering in the Cornell Duffield College of Engineering and a member of the Weill Institute for Cell and Molecular Biology, and jointly led by Noam Zuela-Sopilniak and Julien L. P. Morival in his group. Co-corresponding author Iwijn De Vlaminck is also a professor in the Meinig School.  LMNA-related dilated cardiomyopathy is an inherited heart disease caused by mutations in the LMNA gene, which encodes lamin A and lamin C, proteins that help maintain the structural integrity of a cell’s nucleus. Although researchers have identified a link between LMNA mutations and heart disease, they do not completely understand the cellular mechanisms that lead to heart damage.