Preoperative physical activity linked to lower delirium risk after surgery - News-Medical

Preoperative anxiety affects about 60% of children and is linked with poorer cooperation at anesthesia induction, greater postoperative pain, and maladaptive behavioral changes. Structured play, role play, and medical-themed games can reduce anxiety and improve coping, but many proven approaches rely on digital platforms or virtual reality (VR), which can be costly and hard to implement in busy wards. Those tools may be difficult to adopt in routine practice because of cost, equipment requirements, and implementation burden, especially in busy hospital wards with limited staff and space. Given these challenges, further research is needed to evaluate scalable, low-cost, non-digital play interventions for children that can be delivered widely in routine pediatric surgical care. Researchers at Children's Hospital, Zhejiang University School of Medicine in China reported (DOI: 10.1007/s12519-026-01097-4) the trial online on 19 September 2026 in World Journal of Pediatrics. In the intervention, a trained nurse led a child-life-informed session on the evening before surgery, individually or in groups of up to three children, lasting 40 minutes.

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply. AbstractWhether documented preoperative statin exposure is associated with short-term mortality after aortic valve replacement (AVR) is uncertain. This retrospective multicohort study included 5,291 AVR records from SNUH, MIMIC-IV, and eICU. The primary analysis compared no documented versus any documented statin exposure for recorded 30-day mortality in SNUH and MIMIC-IV using overlap weighting and fixed-effect pooling. Exposure-window, recorded 365-day, IPTW, and SNUH available-follow-up analyses were sensitivity analyses; eICU and agent-specific analyses were exploratory. Overlap-weighted 30-day risks with versus without documented exposure were 1.29% versus 2.55% in SNUH and 1.18% versus 2.36% in MIMIC-IV; the pooled HR was 2.01 (95% CI, 0.98 to 4.11; P = 0.056). A 1-day MIMIC-IV window reclassified seven records and, pooled with the SNUH 24-h definition, yielded an HR of 2.29 (95% CI, 1.14 to 4.61; P = 0.

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