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Votes are being tallied for the 2026 municipal election. Bob Thompson –Something going on in the Prince George area you think people should know about? Send us a news tip by emailing pgnews@vistaradio.ca.

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A protein associated with youth may help aging brain cells regain some of their lost abilities. Scientists at the Icahn School of Medicine at Mount Sinai have discovered that TIMP2 plays an important role in keeping the brain's immune cells healthy, offering new clues about how the brain changes with age. In a study published in Nature Communications, researchers found that removing TIMP2 caused brain immune cells, known as microglia, to develop characteristics linked to aging and neurodegenerative disease. When the scientists restored TIMP2 in the bloodstream of older mice, these cells became better at removing cellular debris and showed fewer molecular signs of inflammation and other potentially harmful changes.

A protein associated with youth may help aging brain cells regain some of their lost abilities. Scientists at the Icahn School of Medicine at Mount Sinai have discovered that TIMP2 plays an important role in keeping the brain's immune cells healthy, offering new clues about how the brain changes with age. In a study published in Nature Communications, researchers found that removing TIMP2 caused brain immune cells, known as microglia, to develop characteristics linked to aging and neurodegenerative disease. When the scientists restored TIMP2 in the bloodstream of older mice, these cells became better at removing cellular debris and showed fewer molecular signs of inflammation and other potentially harmful changes.

Humanity has always had a fascination with conquering nature. We're blessed with the know-how, physical ability, and opposable thumbs to do some truly tremendous stuff. Like transporting oneself through the center of a massive California Redwood, whether by horse-drawn cart or automobile. Even if the population of this monumental icon isn't nearly as vast as it was pre-logging industry, it's possible to still drive through a California Redwood. Such an activity kicked off as a major tourism draw for folks scoping out California and the greater West many years ago, well before the first cross-country American road trip. Back then, it was quite a spectacle to not only find sturdy Sequoias and Redwoods — which are both members of the Cypress family –but also, well, transport oneself through them. In 1878, the first tunnel tree was created in the Tuolumne Grove to draw folks into the Sierra Range, capitalizing on people's interest in Yosemite and every other bit of California's mountainous splendor. A hole was carved in a big ol' Sequoia, now known as Dead Giant. It got this name because it was a 200-foot-tall snag, but it closed in 1993.

Published: October 17, 2026 at 11:25p.m. EDTOttawa Senators defenceman left Saturday’s 3-1 loss to the Philadelphia Flyers after the second period and did not return for the third period. According to head coach Travis Green, the Sens’ captain is nursing an upper-body injury. He appeared to be favouring his right wrist area after a collision with Flyers’ forward Trevor Zegras in the first period. The 29-year-old played 16 shifts and 12:03 TOI before exiting. He was -1 and recorded one shot on goal before exiting. In nine games entering Saturday’s contest, Chabot had one goal and three assists. Over his 578-game career with the Senators, the Sainte-Marie, Que. native has recorded 79 goals and 339 points. The Senators are already without blueliner Jake Sanderson, who has appeared in just one game this season. However, the American Olympian is expected to return in the near future, possibly in time for Wednesday’s date with the Florida Panthers and the return of former captain Brady Tkachuk, according to Post Media’s Bruce Garrioch.

Qingze Gu1, Seyed Alireza Hasheminasab1, Marta Pineda-Moncusí1, Chimweta Chilala2, Johan H. Thygesen3, Honghan Wu3, Sara Khalid1 & CVD-COVID-UK/COVID-IMPACT Consortium We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply.

UFC Edmonton went down on Saturday and offered a violent night of fights and a major main event finish. Adam Martin breaks down an action-packed card that included a record 12 Canadians.

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John Cena says his ex-girlfriend once hit him with her car.

B. C. Votes: Municipal elections 2026LIVEStarted 59 minutes agoVoters in 161 B. C. municipalities go to the polls to elect their next mayor and council, school board and, in some cases, park board. Join hosts Lien Yeung and Stephen Quinn along with Jason D'Souza, Chris Walker and Justin McElroy for live coverage and analysis as results come in from from across the province. October 1811 minutes agoThe watch party begins at Brenda Locke HQ in SurreyKier JunosPeople who support Locke and her Surrey Connect slate mingle at the Mirage Banquet Hall tonight. (Kier Junos/CBC)I’m at Brenda Locke’s election night headquarters with her slate Surrey Connect at the Mirage Banquet Hall in Cloverdale, where the party is just getting started. Plates of fish pakoras, tandoori chicken and hot chai are flying around as Locke’s supporters eat and mingle in a full and bustling room with upwards of 200 people. Many heads are turned toward election night broadcasts on big monitors.

Yannick SchwallerFourthBenoit Schwarz-van BerkelThirdYannick SchwallerSecondSven MichelLeadPablo Lachat-CouchepinCoach: Glenn Howard

Mike Malott left his fellow fighters in awe after knocking out Joaquin Buckley in the UFC Edmonton main event. All the pressure was on Malott to deliver in the main event as he continued his quest to become the UFC’s first Canadian champion since Georges St-Pierre and he rose to the occasion, blasting Buckley with a highlight-reel knee to end their fight in the second round. This is Malott’s fifth straight win and he continues to build his case for a shot at gold following a win over one-time title challenger Gilbert Burns this past April. The MMA community was wowed by Malott’s win, with fighters like Burns, Tatiana Suarez, Arnold Allen, and Kenny Florian reacting in amazement to the brutal knockout. However, UFC featherweight competitor Kai Kamaka added a sobering comment on Twitter, writing “Praying for Buckley,” in reaction to Buckley’s scary collapse to the canvas. See more pros reactions below.

Prime Minister Mark Carney’s nation-building projects will require a strong international talent pool, one put at risk by blunt immigration cuts, says Larissa Bezo of the Canadian Bureau for International Education. Newcomers have been tied, fairly or not, to many of Canadians’ socioeconomic woes in recent years, prompting Ottawa to slam the brakes on the country’s rapid immigration growth. International students were blamed by many Canadians for the affordable housing crisis; foreign workers for depressing wages and stealing jobs; and asylum seekers for draining government resources.