Seizure-Onset Intracerebral Hemorrhage of Undetermined Etiology in a Child: Anesthetic, Intensive Care, and Rehabilitation Management - Cureus

Hemodynamic instability is the most frequent serious complication of tracheal intubation in critically ill adults, and prophylactic vasopressors are increasingly used to prevent it. This systematic review assessed comparative evidence on adrenergic vasopressors given before or during anesthetic induction in adults, with emergency tracheal intubation analyzed as a clinically distinct subgroup. Applicability was examined according to clinical determinants of hemodynamic risk, with procedural location, including urgent radiology, considered as one contextual factor. No protocol was registered. Eligibility was broadened from a radiology-specific population to adult induction and emergency intubation in any setting after preliminary searching found no direct comparative studies. PubMed/MEDLINE, Embase, CENTRAL, and Scopus were searched for studies published from August 2021 to 15 August 2026, with supplementary searching to 26 September 2026. Risk of bias was assessed with risk-of-bias tool for randomized trials (RoB 2) and Risk of Bias in Non-randomised Studies of Interventions (ROBINS-I), and the narrative synthesis followed the Synthesis Without Meta-analysis (SWiM) guideline. Of 341

Hemodynamic instability is the most frequent serious complication of tracheal intubation in critically ill adults, and prophylactic vasopressors are increasingly used to prevent it. This systematic review assessed comparative evidence on adrenergic vasopressors given before or during anesthetic induction in adults, with emergency tracheal intubation analyzed as a clinically distinct subgroup. Applicability was examined according to clinical determinants of hemodynamic risk, with procedural location, including urgent radiology, considered as one contextual factor. No protocol was registered. Eligibility was broadened from a radiology-specific population to adult induction and emergency intubation in any setting after preliminary searching found no direct comparative studies. PubMed/MEDLINE, Embase, CENTRAL, and Scopus were searched for studies published from August 2021 to 15 August 2026, with supplementary searching to 26 September 2026. Risk of bias was assessed with risk-of-bias tool for randomized trials (RoB 2) and Risk of Bias in Non-randomised Studies of Interventions (ROBINS-I), and the narrative synthesis followed the Synthesis Without Meta-analysis (SWiM) guideline. Of 341

Case: In a patient diagnosed with metastatic clear cell RCC, foci observed at very low levels on 18F-FDG PET/CT, and some that were not detectable at all, were seen as dramatically dense on [68Ga]Ga-DPI-4452-PET/CT (carbonic anhydrase IX receptor) imaging. Image courtesy of Prof. Arslan Research was presented at the 39th Annual Congress of the European Association of Nuclear Medicine (EANM’26)

AcknowledgementsThe authors thank Arcus Biosciences for providing AB680 and AB928 for the experiments. This research was supported [in part] by the Intramural Research Program of the National Institutes of Health (NIH), National Cancer Institute, CCR, CIL. The contributions of the NIH authors (S. T., C. I. K. C., F. J. G.) were made as part of their official duties as NIH federal employees, are in compliance with agency policy requirements, and are considered Works of the United States Government. However, the findings and conclusions presented in this paper are those of the authors and do not necessarily reflect the views of the NIH or the U. S. Department of Health and Human Services. Schematic diagrams (Figs. 1A, E, 2A, E, 5D, 6A, D and 7A, G) were created with BioRender.com. FundingThis work was funded by NIH grants R01CA148828, R01CA245546, R01DK095201, and UMCCC Core Grant P30CA046592 (Y. M. S.). R01AI152517 to C. A. P. R01CA248160 to C. A. L. R. S. was supported by a Postdoctoral Fellowship (032650) from the American Physiological Society and a Research Fellow Award (1003279) from the Crohn’s and Colitis Foundation. N. W. Z.