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A technology developed at The University of Queensland allowing scientists to observe how disease-related proteins behave inside living neurons will be used to advance early drug discovery for neurodegenerative diseases. The NASTIC (Nanoscale Spatiotemporal Indexing Clustering) platform, spun out into Brisbane-based startup Accretion Bio, enables researchers to study real-time biological processes in living cells across space and time at the single-molecule level for the first time.

For some cancer patients, the effects of immunotherapy can linger in an unexpected place: their joints. Painful arthritis may return repeatedly, sometimes becoming more severe with each episode. Now, scientists have uncovered a possible explanation involving the immune system's ability to remember previous attacks. Researchers at The University of Texas MD Anderson Cancer Center have found evidence that arthritis triggered by certain cancer immunotherapies behaves like a disease driven by immune memory. Rather than launching an entirely new inflammatory response during each flare, the immune system appears to reactivate cells involved in earlier episodes.

A fossil theropod vertebra about the length of a thumb, found in the Algarve region in southern Portugal, may be the oldest dinosaur remains ever discovered on the Iberian Peninsula. An artist’s impression of Sarcosaurus. Image credit: TotalDino / CC BY 4.0.