Mental health as both outcome and determinant in climate adaptation - Nature

Endogenous endophthalmitis is an aggressive intraocular infection with a characteristically poor visual prognosis. We present a 55-year-old Malay woman with suboptimally controlled diabetes mellitus who developed sepsis from a liver abscess. Following the isolation of Klebsiella pneumoniae from the abscess drainage, which demonstrated susceptibility to gentamicin and trimethoprim-sulfamethoxazole, she was commenced on targeted systemic antimicrobial therapy. During her admission, she reported a sudden visual decline in her left eye, with visual acuity decreasing to 6/21. Clinical examination of the left eye revealed anterior chamber inflammation with a hypopyon, alongside pronounced vitritis and retinitis, while the right eye remained entirely unaffected. Recognizing this as Klebsiella pneumoniae endogenous endophthalmitis, we immediately performed a vitreous tap and injected intravitreal vancomycin and ceftazidime, proceeding to a trans pars plana vitrectomy (TPPV) with repeat intravitreal antibiotics the following day. Although her vitreous fluid cultures returned negative, the infection resolved on a postoperative regimen of topical 0.5% moxifloxacin, systemic ciprofloxacin, and

On September 16, the Plenary of the Boao Forum for Asia Global Health Forum 2026 Haikou Conference was held in Haikou, Hainan Province. Liang Zhenying, Vice Chairman of the 14th National Committee of the Chinese People's Political Consultative Conference, attended and addressed the Plenary. Other speakers included Shen Hongbing, Vice Health Minister of the National Health Commission and Administrator of the National Disease Control and Prevention Administration; Sardar Md. Sakhawat Husain, Minister for Health and Family Welfare, The People's Republic of Bangladesh; Bounserth Keoprasith, Vice Minister of Health, The Lao People’s Democratic Republic; Yang Sheng, Deputy Director General, National Medical Products Administration; Mohamed Ahmed Abdelhakim Melegy, Head of Central Administration for Therapeutic Affairs, Ministry of Health and Population, The Arab Republic of Egypt; Hans Kluge, WHO Regional Director for Europe; Xie Jing, Vice Governor of Hainan Province. Shen Hongbing and Richard Remington, Senior Vice President of Elsevier Cell Press, delivered keynote speeches. Zhang Jun, Secretary General of Boao Forum for Asia, moderated the Opening Remarks session.

AcknowledgementsThe authors thank Arcus Biosciences for providing AB680 and AB928 for the experiments. This research was supported [in part] by the Intramural Research Program of the National Institutes of Health (NIH), National Cancer Institute, CCR, CIL. The contributions of the NIH authors (S. T., C. I. K. C., F. J. G.) were made as part of their official duties as NIH federal employees, are in compliance with agency policy requirements, and are considered Works of the United States Government. However, the findings and conclusions presented in this paper are those of the authors and do not necessarily reflect the views of the NIH or the U. S. Department of Health and Human Services. Schematic diagrams (Figs. 1A, E, 2A, E, 5D, 6A, D and 7A, G) were created with BioRender.com. FundingThis work was funded by NIH grants R01CA148828, R01CA245546, R01DK095201, and UMCCC Core Grant P30CA046592 (Y. M. S.). R01AI152517 to C. A. P. R01CA248160 to C. A. L. R. S. was supported by a Postdoctoral Fellowship (032650) from the American Physiological Society and a Research Fellow Award (1003279) from the Crohn’s and Colitis Foundation. N. W. Z.

RSV IN lung transplant recipients was associated with respiratory failure, declining lung function, and mortality in hospitalized patients. An international multicenter study of 155 adult lung transplant recipients hospitalized with respiratory syncytial virus (RSV) infection identified clinical predictors of severe complications, highlighting the importance of early assessment and continued monitoring in this vulnerable population.