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Huntington's disease is caused by repetitive "stutters" in DNA—specifically repeated CAG sequences—that expand abnormally over time, leading to toxic protein accumulation that contributes to the progression of the disease. There is currently no cure for this rare and fatal genetic disease. Professor Vincent Dion of the UK Dementia Research Institute at Cardiff University, who led the research team, said, "The length of these repeated sequences accounts for most of the variation in how severe the disease is, so targeting and reducing these sequences is a potentially viable therapeutic avenue.

Menopausal brain fog is common, and hormone therapy has neutral cognitive effects, according to Pauline M. Maki, PhD. Between 40% and 60% of women reported brain fog or forgetfulness during the menopause transition, according to Pauline M. Maki, PhD, who presented on cognitive changes in midlife at the Menopause Society 2026 Annual Meeting. Misinformation on social media and exaggerations of the current science led many patients to fear these symptoms signaled the beginning of Alzheimer disease—which, next to breast cancer, is the disease women fear most. For that reason, Maki recommends that clinicians first normalize the complaint. A second key role for clinicians is distinguishing cognitive changes that are a natural part of the menopause transition from cognitive changes associated with dementia. Dementia at midlife is very rare, noted Maki, a professor of Psychiatry, Psychology and Obstetrics & Gynecology; director of Women’s Mental Health Research Program; and senior director of research, Center for Research on Women and Gender, University of Illinois College of Medicine, Chicago.

DR Congo Ebola cases near 10,000: WHOOf the 66 health zones affected to date, 50 reported at least one new confirmed case during the most recent 21 days, according to a report. The disease caused by the Bundibugyo virus strain has affected eight provinces. Ebola transmission in the Democratic Republic of Congo has remained active in more than three-quarters of all health zones affected since the start of the outbreak in May, the World Health Organization's (WHO) Africa regional office said in a situation report Wednesday, as the cumulative caseload neared 10,000. The disease caused by the Bundibugyo virus strain has affected eight provinces: Haut-Uele, Ituri, North Kivu, South Kivu, Bas-Uele, Tshopo, South-Ubangi and North Ubangi. The number of confirmed Ebola cases in Congo has surpassed 9,600, including 4,646 deaths since the outbreak was declared, according to WHO data. Of the 66 health zones affected to date, 50, or 75.8%, reported at least one new confirmed case during the most recent 21 days, the report showed.

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Consistent bedtime routines, screen-free bedrooms and therapist support for night waking help children with ADHD sleep better, said Alison Pritchard, Ph. D. Structure is the first step toward better sleep for children with ADHD, according to Alison Pritchard, Ph. D., a child clinical psychologist and co-director of the Center for Neuropsychological and Psychological Assessment at Kennedy Krieger Institute in Baltimore. “I think number one is just having a schedule and sticking to it is really helpful,” she said. “As in many areas of life for kids with ADHD, having a bit more structure can be helpful.”For children who have trouble falling asleep, a bedtime routine done “the same way, at the same time, every night” can make a substantial difference in sleep onset, she said. She also recommends removing phones, TVs and video games from the bedroom because they are too tempting. “Most of us adults have a hard time getting off our phones when it’s time to go to bed at night,” Pritchard said. “So, kids can’t be expected to do that for themselves.”For children who wake at night and have difficulty falling back asleep, Pritchard suggests working with a counselor or therapist.