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Science

Unprecedented atlas explores mitochondria across the tree of life - Nature

The protein catalogue gives a dynamic picture of the mitochondria, beyond what was known from humans and yeast. Credit: Dr David Furness/Keele University/SPLScientists have mapped in unprecedented detail the proteins that make up the mitochondria in six organisms — five single-celled parasites and one plant — spanning the eukaryotic tree of life. The findings, described in nine papers published in Cell, Cell Press Blue, Molecular Cell and Current Biology on 1 October1–9, reveal dozens of proteins that are not found in humans but are shared among parasites, including some that cause malaria or sleeping sickness. The findings might help scientists to devise new treatments for these illnesses. The work has also stirred a long-running debate about the origin of the mitochondrion. Cells are swapping their mitochondria. What does this mean for our health? Best known as the powerhouse of the eukaryotic cell because it produces energy, the mitochondrion has its own tiny DNA, which is distinct from that of the cell’s nucleus. But both mitochondrial and nuclear DNA encode the proteins that make up this organelle.

Nature·
Science

NASA’s ISS Crew-12 Reflects On Their Lengthy ISS Mission - Aviation Week

HOUSTON—As the International Space Station (ISS) prepares to mark 26 years of continuous occupancy by astronauts and cosmonauts on Nov. 2, its latest returnees offered perspective about life onboard the orbital lab. The facility is counting down to a planned safe deorbit by the end of 2030 after... Mark CarreauMark is based in Houston, where he has written on aerospace for more than 25 years. While at the Houston Chronicle, he was recognized by the Rotary National Award for Space Achievement Foundation in 2006 for his professional contributions to the public understanding of America's space program through news reporting.

Aviation Week·
Science

New dinosaur species identified from fossil tucked away in a museum - Yahoo News Canada

(NewsNation) — A fossil stored in a London museum for more than a century has been identified as a new species of dinosaur. Researchers say the new dinosaur, Invictibellatrix amberina, was identified from a skull fragment at the Natural History Museum. The fossil was first found by Reginald Walter Tooley, an amateur paleontologist, at the base of a cliff on the Isle of Wight. After Tooley died, the museum acquired the fossil in 1924, along with more than 1,000 other specimens he had collected. "It is a real mystery that this fossil was overlooked for so long, sitting in a drawer for nearly 100 years," said the study's lead author, Dr. Cassius Morrison, in a press release. Researchers used CT scans to make 3D images of the skull and the area where the dinosaur's brain would have been. When they compared these images to other meat-eating dinosaurs, they found some unusual features. These included an oval-shaped opening where the spinal cord met the brain and a ridge shaped like an hourglass. These differences led them to decide it was a new species. Invictibellatrix was part of a group of meat-eating dinosaurs called megaraptorans, which were related to tyrannosaurs.

Yahoo News Canada·
Science

Deleting AI chats may not erase every trace - Futurity

Deleting a conversation with an artificial intelligence (AI) assistant may not erase everything the assistant remembers. Georgia Tech researchers have developed a tool that can recover deleted conversations from AI assistants running on Android phones. The tool, called ORISA, can also rebuild the recovered information into a working AI session.

Futurity·
Science

Metabolic characteristics and evolutionary history of the nitrogen-fixing cyanobacterial endosymbionts of pennate diatoms - Nature

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply. AbstractNitrogen-fixing cyanobacteria are important sources of bioavailable nitrogen on Earth. Some nitrogen-fixing cyanobacteria are endosymbionts of algae, and recently one of them, UCYN-A2, was shown to be an early-stage organelle (nitroplast) of haptophytes. These biological associations are important models for studying co-evolution and organellogenesis. Endosymbioses between Rhopalodiaceae diatoms and nitrogen-fixing cyanobacteria (spheroid bodies, SBs) are widespread in marine and freshwater ecosystems, but their adaptation and evolution remain unclear. We found that the genomes and metabolic characteristics of marine and freshwater SBs are remarkably similar. Purifying selection pressures dominated SB diversification both within marine and freshwater habitats and across habitat boundaries.

Nature·
Science

Reliability and validity of the one-minute sit-to-stand test in Parkinson’s disease - Nature

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply. AbstractTo investigate the validity and test–retest reliability of the One-Minute Sit-to-Stand Test (1STS) in individuals with Parkinson’s disease (PD). Twenty-eight individuals with PD performed the 1STS twice with a 7-day interval. Concurrent validity was examined using correlations with the 2-Minute Walk Test (2MWT) and the Hoehn and Yahr (H&Y) stage. Test–retest reliability was assessed using the intraclass correlation coefficient (ICC). The 1STS showed a strong positive correlation with the 2MWT (r = 0.69, p < 0.01) and a moderate negative correlation with the H&Y stage (r = − 0.58, p < 0.01). Test–retest reliability was excellent (ICC = 0.94, 95% CI: 0.86–0.97). The 1STS is a reliable and potentially valid measure of functional performance in individuals with PD. It may be considered a practical option in clinical settings; however, further research is needed to confirm these findings.

Nature·
Science

Ancient fungus unlocks secret support system in major food crops that could transform farming practices - Phys.org

Arabidopsis thaliana, a small flowering mustard plant used worldwide as the primary genetic model in plant biology, was long believed incapable of forming relationships with underground fungal networks. New research published in Current Biology led by professor Katie Field demonstrates for the first time that it can establish a fully functional, resource-sharing partnership with an ancient soil fungus known as a Mucoromycotina fine root endophyte (MFRE).

Phys.org·