Health

“More important survivorship research being presented at American Society of Clinical Oncology (ASCO) – ASCOQLTY26! Excited to highlight two studies led by Niharika Dixit and colleagues that reinforce an essential component of high-quality survivorship care: We must first identify the needs of cancer survivors to effectively address them!

“This expanding partnership is strategically significant, broadening the depth and diversity of research disciplines we can apply to cancer challenges and enabling our research to involve even larger, more diverse patient populations across London and the South East. Dr. Barbara Pittam, our Chief Research and Academic Officer, attended the Imperial College Academic Health Science Centre meeting this week on behalf of the ICR.

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply. AbstractPredicting photovoltaic power generator outputs is not easy, especially when the values are near zero, because even very small errors can lead to large percentage errors. We introduce a new forecasting framework, ZAPP (Zero-Aware Photovoltaic Power Predictor), that handles near-zero errors while maintaining high prediction accuracy. The model does not rely on a single unified regression model but instead attaches two refinement stages to a base regression model. The first stage, called ZeroGate, predicts whether the output should be zero. The second refinement stage, the low-power MAPE reducer, fine-tunes the non-zero outputs near the zero level without significantly affecting scale-dependent regression metrics.

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply. AbstractDelirium is a common but frequently underrecognized neuropsychiatric syndrome among older adults in the emergency department (ED), associated with prolonged hospitalization and increased mortality. To develop a clinical risk score for early delirium detection in older emergency department patients. We conducted a prospective cohort study in the ED of a tertiary hospital from July 2024 to July 2025. Patients aged ≥ 65 years who remained in the ED for > 4 h were assessed using the Thai version of the Confusion Assessment Method intensive care unit (CAM-ICU) within 12 h of arrival. Demographic data, comorbidities, functional status, medications, presenting features, vital signs, laboratory values, and ED diagnoses were collected. Multivariable logistic regression was used to derive a clinical risk score, which was evaluated area under the receiver operating characteristic curve (AuROC).

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply. AbstractThis study was conducted to determine the effect of Endometriosis Nursing Care Program (ENCP), developed in line with Health Promotion Model for women with endometriosis, on women's quality of life and healthy lifestyle behaviours. This prospective, single-centre, randomized controlled trial was conducted with 46 women diagnosed with endometriosis who applied to the Endometriosis Outpatient Clinic of a training research hospital. Women with an Endometriosis Health Profile Questionnaire-5 (EHP-5) score ≥ 22 indicating reduced quality of life were included. Participants were randomly assigned to an intervention group (n = 23) receiving Endometriosis Nursing Care Program (ENCP) or a control group (n = 23) receiving routine care. The ENCP consisted of two individual 60-min sessions delivered two weeks apart. The primary outcome was change in quality of life measured by EHP-5.

, Alexandra Mae Jones | CBC News | Posted: October 17, 2026 8:00 AM | Last Updated: 2 hours agoWith more than 9,200 confirmed cases and 4,400 deaths, children are vulnerable 'on so many levels'Image | DR Congo Ebola ChildrenCaption: Congolese medical workers dressed in personal protective equipment carry children tested for Ebola inside a secured Ebola response zone in Bunia, D. R. C., on June 9. An estimated 1,900 children have been separated from their caregivers because of the disease. (Gradel Muyisa Mumbere/Reuters)Outside of a treatment centre for Ebola in a northeastern corner of the Democratic Republic of Congo, as the country battles its worst outbreak on record, Neema Nyaloka bounces a baby on her lap. Nyaloka survived Ebola herself. Now, she works with UNICEF to take care of the droves of children isolating from their parents who are being treated for it. UNICEF is operating 12 other child-care centres next to treatment centres full of Ebola patients. Some kids are waiting for their parents to recover, but others have been left stranded after family members passed away.

RSV vaccination was associated with substantially lower all-cause mortality among older adults with heart failure in a multicenter, propensity-matched analysis of U. S. electronic health records. Researchers identified adults aged 60 years or older with heart failure and compared outcomes according to respiratory syncytial virus vaccination status. After propensity score matching, 777 vaccinated patients and 777 unvaccinated patients had well-balanced baseline demographic characteristics, comorbidities, and medication use.

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply. AbstractAlthough retinal fundus imaging is a non-invasive tool to assess systemic and fundus pathology, current deep learning algorithms are mostly single-task, lack clinical interpretability and are unable to handle acquisition variation between different domains. These constraints limit their clinical utility: when a patient comes to the clinic for fundus screening, they could also be diabetic, have glaucoma, AMD, and increased cardiovascular risk, with each disease having retinal vascular biomarkers that require a patient to be tested for in the clinic, which must be managed within a framework of common, interpretable, and generalizable models rather than a pipeline of independent models.

Fibrosis, the dense scar tissue that can entangle peritoneal tumors and the healthy organs around them, is one reason cytoreduction surgery is denied to a portion of patients with appendiceal and other abdominal cancers. Allegheny Health Network Cancer Center’s newly launched RANDY’S Trial is built on a direct answer to that problem: test whether FDA-approved drugs already on the market can remodel that scar tissue and bring more patients into surgical eligibility. The trial did not emerge from a pharma pipeline or an NIH grant. A single community gala, the La Sera d’Oro event, raised $44,000 in 2025 to fund it. The acronym stands for Repurposed And Naturally-Derived Drugs for the Treatment of Fibrosis in Peritoneal Carcinomatosis. Principal investigator Patrick Wagner, a surgical oncologist at AHN, is leading a multidisciplinary team that will evaluate existing medications for their ability to break down or remodel abdominal scar tissue. The mechanism matters because fibrosis does two things that complicate surgery: it obscures the boundary between healthy and diseased tissue, and it can trap cancer cells that are then left behind when a surgeon separates planes.

Online event offers support for menopause and pain2 hours agoHannah Mitchell, North East and CumbriaandStephanie Finnon, BBC Radio CumbriaPA MediaSouth Cumbria support group Menopause Matters is inviting people from across the county to share their experiencesA support group is holding a county-wide event for women coping with pain associated with menopause and perimenopause. South Cumbria support group Menopause Matters is holding an online forum for World Menopause Day, inviting people to share their experiences and ask questions. World Menopause Day is an annual event started by the International Menopause Society (IMS), with this year's theme Chronic Pain At Midlife. Facilitator Leigh Williams said she hoped Sunday's free online event, being held between 19:00 and 20:00 BST, would "open up the conversation" around pain and menopause. Menopause Matters also holds a monthly cafe-style drop-in in Barrow-in-Furness, offering women the opportunity to meet up in an informal environment. Williams was inspired to become a facilitator because of her own experience with perimenopause and chronic pain. "I know what it feels like when pain starts to shrink your world," she said.

Infection with the human papillomavirus (HPV) is extremely common and, in the vast majority of cases, clears up on its own. However, in some people, the infection persists and can develop into precancerous lesions or even cancer. How can these high-risk situations be identified at an early stage? This is the central question of a study conducted by Michael Herfs’s team at the Interdisciplinary Biomedical Research Center GIGA’s Laboratory of Experimental Pathology at the University of Liège, published in Trends in Molecular Medicine. For several decades, researchers have sought to identify biomarkers capable of accurately predicting the outcome of an infection with a high-risk oncogenic HPV type. Despite significant advances, no viral, immune-related, or molecular marker can currently and reliably predict which infections will regress spontaneously and which will progress to more severe disease.