Development and internal validation of a clinical risk score for early delirium detection in older emergency department patients - Nature
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AbstractDelirium is a common but frequently underrecognized neuropsychiatric syndrome among older adults in the emergency department (ED), associated with prolonged hospitalization and increased mortality. To develop a clinical risk score for early delirium detection in older emergency department patients. We conducted a prospective cohort study in the ED of a tertiary hospital from July 2024 to July 2025. Patients aged ≥ 65 years who remained in the ED for > 4 h were assessed using the Thai version of the Confusion Assessment Method intensive care unit (CAM-ICU) within 12 h of arrival. Demographic data, comorbidities, functional status, medications, presenting features, vital signs, laboratory values, and ED diagnoses were collected. Multivariable logistic regression was used to derive a clinical risk score, which was evaluated area under the receiver operating characteristic curve (AuROC).
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