What are the legal considerations for Canadian employers requiring cross-border travel in the Trump era? - Benefits Canada.com

Amphetamine-associated rhabdomyolysis is an uncommon but potentially life-threatening condition. Massive release of myoglobin and intracellular electrolytes may result in severe metabolic, cardiovascular, and renal complications, particularly acute kidney injury (AKI). We report two cases of severe amphetamine-associated rhabdomyolysis complicated by dialysis-requiring AKI. The first patient, a 46-year-old man, presented with a serum creatine kinase (CK) level of 947,699 U/L, serum creatinine of 734 µmol/L, hyperkalemia of 6.8 mmol/L, and transient left ventricular systolic dysfunction. Management consisted of supportive therapy and eleven sessions of intermittent hemodialysis. The clinical course was complicated by severe delayed hypercalcemia (4.10 mmol/L), followed by cardiac arrest and death. The second patient, a 42-year-old man, presented with a serum CK level of 525,796 U/L, serum creatinine of 544 µmol/L, and hyperkalemia of 7.5 mmol/L. He received supportive treatment and ten sessions of intermittent hemodialysis, resulting in near-complete recovery of renal function. Urine toxicology screening was positive for amphetamines in both patients. Alternative traumatic and non-t

Amphetamine-associated rhabdomyolysis is an uncommon but potentially life-threatening condition. Massive release of myoglobin and intracellular electrolytes may result in severe metabolic, cardiovascular, and renal complications, particularly acute kidney injury (AKI). We report two cases of severe amphetamine-associated rhabdomyolysis complicated by dialysis-requiring AKI. The first patient, a 46-year-old man, presented with a serum creatine kinase (CK) level of 947,699 U/L, serum creatinine of 734 µmol/L, hyperkalemia of 6.8 mmol/L, and transient left ventricular systolic dysfunction. Management consisted of supportive therapy and eleven sessions of intermittent hemodialysis. The clinical course was complicated by severe delayed hypercalcemia (4.10 mmol/L), followed by cardiac arrest and death. The second patient, a 42-year-old man, presented with a serum CK level of 525,796 U/L, serum creatinine of 544 µmol/L, and hyperkalemia of 7.5 mmol/L. He received supportive treatment and ten sessions of intermittent hemodialysis, resulting in near-complete recovery of renal function. Urine toxicology screening was positive for amphetamines in both patients. Alternative traumatic and non-t

Agoda has “doubled” its supply of premium accommodation over the past four years, Andrew Smith, senior vice president of supply at the Booking Holdings-owned online travel agency, told Skift. Recent deals with luxury groups show how Agoda is adding that inventory.

Some Vrbo listings will be allowed to keep their annual subscriptions even as Vrbo ends its legacy subscription model on October 29, Skift has learned. They include some users of Vrbo’s in-house Escapia property management system, as well as others not on Escapia. Most listings on annual plans will be required to move to a 12% commission on each booking when their plans expire. The subscription can cost less than that for some hosts, and some hosts and homeowners have expressed concern about the change.

Various countries have updated their travel guidance as cost-of-living protests continue in France and neighboring countries. Hundreds of thousands of people in France took to the streets over the weekend to protest rising expenses and school conditions, with some demonstrations turning violent. At least 2,000 people have been arrested and more than 600 law enforcement officers and firefighters have been injured amid these scenes of violence, Laurent Nuñez, France’s minister of the interior, said Sunday.