Additional Maryland State Parks Requiring Day-Use Reservations; New Entrance Technology Starting This Weekend - Maryland.gov

Amphetamine-associated rhabdomyolysis is an uncommon but potentially life-threatening condition. Massive release of myoglobin and intracellular electrolytes may result in severe metabolic, cardiovascular, and renal complications, particularly acute kidney injury (AKI). We report two cases of severe amphetamine-associated rhabdomyolysis complicated by dialysis-requiring AKI. The first patient, a 46-year-old man, presented with a serum creatine kinase (CK) level of 947,699 U/L, serum creatinine of 734 µmol/L, hyperkalemia of 6.8 mmol/L, and transient left ventricular systolic dysfunction. Management consisted of supportive therapy and eleven sessions of intermittent hemodialysis. The clinical course was complicated by severe delayed hypercalcemia (4.10 mmol/L), followed by cardiac arrest and death. The second patient, a 42-year-old man, presented with a serum CK level of 525,796 U/L, serum creatinine of 544 µmol/L, and hyperkalemia of 7.5 mmol/L. He received supportive treatment and ten sessions of intermittent hemodialysis, resulting in near-complete recovery of renal function. Urine toxicology screening was positive for amphetamines in both patients. Alternative traumatic and non-t

Amphetamine-associated rhabdomyolysis is an uncommon but potentially life-threatening condition. Massive release of myoglobin and intracellular electrolytes may result in severe metabolic, cardiovascular, and renal complications, particularly acute kidney injury (AKI). We report two cases of severe amphetamine-associated rhabdomyolysis complicated by dialysis-requiring AKI. The first patient, a 46-year-old man, presented with a serum creatine kinase (CK) level of 947,699 U/L, serum creatinine of 734 µmol/L, hyperkalemia of 6.8 mmol/L, and transient left ventricular systolic dysfunction. Management consisted of supportive therapy and eleven sessions of intermittent hemodialysis. The clinical course was complicated by severe delayed hypercalcemia (4.10 mmol/L), followed by cardiac arrest and death. The second patient, a 42-year-old man, presented with a serum CK level of 525,796 U/L, serum creatinine of 544 µmol/L, and hyperkalemia of 7.5 mmol/L. He received supportive treatment and ten sessions of intermittent hemodialysis, resulting in near-complete recovery of renal function. Urine toxicology screening was positive for amphetamines in both patients. Alternative traumatic and non-t

Honda have unveiled an all-new middleweight sportsbike called the CBR500R Four, built around a brand-new 502cc inline four-cylinder engine, with standard-fit E-Clutch. The new bike, distinguished from the parallel-twin CBR500R by its ‘Four’ suffix, costs just £6999 – £100 more than the twin – and will be available from January 2027.

EXCLUSIVE: Soccer YouTuber Eman SV2, whose channel has 6 million subscribers, is launching a creator company. Eman SV2, whose real name is Eman Balogun (no relation to American soccer star Folarin Balogun), is opening Frenzy, which he said will operate in content, commerce and live experiences. The company launches in a few days’ time and has five staff plus freelancers and coaches for live events.