Feeding and fasting reveal appetite-linked genes in Siberian sturgeon | Newswise - Newswise
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Newswise — Fish rely on signals from the brain and other organs to balance food intake with their energy needs. One such signal, melanin-concentrating hormone (MCH), was first discovered in salmon and has since been studied across vertebrates. In mammals, MCH generally promotes eating, but studies in fish have produced mixed results: its associated gene appears to respond differently to feeding and fasting in different species. Siberian sturgeon are widely farmed for meat and caviar, yet little was known about their pmch genes, where those genes are active, or how they respond when food becomes available or scarce. A study (DOI: 10.48130/jai-0026-0004) published in Journal of Applied Ichthyology on 30 July 2026 by Zhiqiong Li's & Ni Tang's team, Chengdu Agricultural College, reports two pmch forms whose expression patterns suggest possible roles in appetite regulation and liver energy metabolism. The researchers first isolated and sequenced two pmch transcripts, named pmcha and pmchb, from Siberian sturgeon. Their sequences encode precursor proteins of 179 and 158 amino acids, respectively.
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