Congo’s Ebola outbreak leaves grieving families struggling with fear and stigma - SooLeader.com

BUNIA, Congo (AP) — When a schoolteacher in eastern Congo learned that five of her family members had been diagnosed with Ebola, she was “deeply shaken,” fearing the worst from

New studies of trends in the global burden of measles and pertussis offer a reminder of how much vaccination has achieved and a warning of the need to build more resilient and sustainable vaccination programs. This is a preview of subscription content, access via your institution

Chronic airway infection and inflammation form a destructive partnership in cystic fibrosis. Recent evidence shows that Pseudomonas aeruginosa persistent infections can redirect immunity towards tissue injury. Access Nature and 54 other Nature Portfolio journals

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply. AbstractMonascin (MS) and ankaflavin (AK) are bioactive yellow pigments produced by Monascus species, known for their health benefits and safety profile compared to monacolin K. This study developed an integrated strategy combining Response Surface Methodology (RSM) for submerged fermentation optimization and a downstream purification process to maximize MS and AK production by Monascus purpureus TST. Although the results of this study demonstrate that RSM did not successfully predict the optimal production conditions, the RSM optimization revealed significant interactions between sucrose, ammonium sulfate, and magnesium sulfate heptahydrate. Verification experiments confirmed that the optimal culture conditions for M. purpureus TST were 200 g/L sucrose, 17.5 g/L (NH4)2SO4, and 0.1 g/L MgSO4·7H2O.