Architectural swarms for responsive façades and creative expression - Science | AAAS

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply. AbstractCovalent organic frameworks (COF) have emerged as promising phototherapeutic platforms for tumor therapy, where the columnar π-arrayed metal-free photosensitizers serve as both a cooperative light-harvesting antenna and a semiconducting scaffold for efficient charge-carrier separation and transport. However, the phototherapeutic agents based on COFs are usually activated with ultraviolet and visible light, resulting in the limitation of deep-tissue phototherapy. Herein, we develop near-infrared-responsive COFs through elaborate design and synthesis of a thia-hexaphyrin building block, which feature well-aligned conjugation skeletons for the generation of reactive oxygen species (ROS) and photothermal effect upon 808 nm laser irradiation, outperforming conventional porphyrin-based COFs.

Recent Listeria outbreaks have many Canadians paying closer attention to food recalls while grocery shopping. Fresh produce, cheeses and deli meat are high-risk foods often contaminated by harmful bacteria. According to the World Health Organization, unsafe food causes 866 million illnesses and 1.5 million deaths annually, highlighting the need for innovative approaches to improve food safety. Henry Abanum, a Master of Science in Pharmacy student, aims to address this challenge by developing a bacteria-responsive coating for food contact materials that integrates toxin detection with on-demand antimicrobial delivery. Henry Abanum (he/him), Master of Science in Pharmacy student