An AI-based symptom checker integrated into MomConnect maternal healthcare platform: a prospective, observational mixed-methods study - Nature

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply. AbstractThis study aimed to evaluate the associations of phubbing with fear of childbirth and early maternal–infant bonding among term pregnant women who delivered vaginally. This single-center prospective observational study included 75 women with term pregnancies (37–42 weeks) who delivered vaginally. The Wijma Delivery Expectancy/Experience Questionnaire-A (W-DEQ A) and Generic Scale of Phubbing (GSP) were administered before active labor, and the Mother-to-Infant Bonding Scale (MIBS) was completed on postpartum day 2. MIBS items were recoded so that higher scores indicated more favorable bonding. Associations were assessed using Spearman correlation and multiple linear regression with heteroskedasticity-consistent HC3 standard errors. The mean age was 27.1 ± 4.3 years.

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply. AbstractWhether documented preoperative statin exposure is associated with short-term mortality after aortic valve replacement (AVR) is uncertain. This retrospective multicohort study included 5,291 AVR records from SNUH, MIMIC-IV, and eICU. The primary analysis compared no documented versus any documented statin exposure for recorded 30-day mortality in SNUH and MIMIC-IV using overlap weighting and fixed-effect pooling. Exposure-window, recorded 365-day, IPTW, and SNUH available-follow-up analyses were sensitivity analyses; eICU and agent-specific analyses were exploratory. Overlap-weighted 30-day risks with versus without documented exposure were 1.29% versus 2.55% in SNUH and 1.18% versus 2.36% in MIMIC-IV; the pooled HR was 2.01 (95% CI, 0.98 to 4.11; P = 0.056). A 1-day MIMIC-IV window reclassified seven records and, pooled with the SNUH 24-h definition, yielded an HR of 2.29 (95% CI, 1.14 to 4.61; P = 0.

Introduction: Laparoscopic cholecystectomy is the standard surgical treatment for symptomatic cholelithiasis, but a proportion of patients continue to experience abdominal or gastrointestinal symptoms after surgery. This study evaluated the frequency of persistent symptoms and the resolution pattern of individual gastrointestinal symptoms following laparoscopic cholecystectomy. Methods: This prospective longitudinal observational study was conducted at Pushpagiri Institute of Medical Sciences and Research Centre, Thiruvalla, Kerala. Eligible patients undergoing laparoscopic cholecystectomy for symptomatic cholelithiasis were prospectively enrolled and followed for one to six months after surgery through outpatient visits or telephone follow-up. Symptoms were recorded using a predefined structured proforma; no separate validated gastrointestinal symptom score was used. Of 70 enrolled patients, four who underwent open cholecystectomy were excluded, and eight were lost to follow-up, leaving 58 patients for final analysis. Paired preoperative and postoperative symptom status was compared using the exact McNemar test. Results: Among the 58 patients who completed follow-up, 39 were femal