Health

● Clinical Trial Application planned for filing with Health Canada, extending the Company’s international regulatory strategy for gout program XRx-026 ●CALGARY, Alberta, Oct. 08, 2026 (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (“XORTX” or the “Company”) (NASDAQ: XRTX), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide an outline of its anticipated Clinical Trial Application (“CTA”) submission to Health Canada for the XRx-026 gout program. The filing supports the Company’s planned two-part clinical study, XRX-OXY-102, evaluating XORLOTM, the Company’s proprietary formulation of oxypurinol, a xanthine oxidase inhibitor, for the treatment of gout. Conducting the first part of the XRX-OXY-102 clinical study in Canada is expected to enable the Company to accelerate the delivery of key clinical data in support of its planned New Drug Application (“NDA”) filing with the U. S. Food and Drug Administration (the “FDA”) for marketing approval. Recent drug development team activities have included parallel preparation of the CTA for filing with Health Canada.

IntroductionCreativity, broadly defined as the ability to form novel and valuable ideas or to find new solutions to problems [1], has long been suggested to be associated with psychiatric disorders [2]. This idea is fueled by many anecdotal examples of famous creators with eccentric personalities and psychiatric problems, from Vincent van Gogh and Ernest Hemingway to Virginia Woolf and Camille Claudel [3]. More recently, research including some systematic reviews and meta-analyses, has suggested that creativity and engagement in creative activities are associated with an increased risk of mental health problems [4, 5]. For example, creative professions were associated with a higher risk of bipolar disorder [6], music playing with more psychosis-like experiences [7, 8], and artistic achievement with multiple mental disorders [9]. However, the literature shows inconsistencies. For example, Cuypers et al. [10] found music-related creative activities to be associated with better perceived mental health. Similarly, art-related cultural activities were associated with less depression in older adults [11] and more social well-being in young adults [12].

HomeNewsUpdates to Medical Transportation Benefit client forms October 8, 2026FNHA infoBenefits The First Nations Health Authority (FNHA) is committed to providing accessible, efficient, and Client-centered services. As part of this commitment, Medical Transportation (MT) Client forms have been updated to reflect current program operations, make them easier to complete and help streamline the processing of travel requests and reimbursements.

HomeNewsThe 2026-2027 Winter Wellness Grants are now open! October 8, 2026NewsFNHA Apply by October 28 to receive funding to support community winter wellness

The NDP government is finally putting more money into one of the most important solutions to Manitoba’s emergency-room crisis: getting patients who no longer require acute-care treatment out of hospitals and into more appropriate care. *Billed as $5.77 plus GST every four weeks. After 52 weeks, price increases to the regular rate of $19.95 plus GST every four weeks. Offer available to new and qualified returning subscribers only. Cancel any time.

If you or someone you know needs help, call or text 988 to reach the Suicide and Crisis Lifeline or live chat at https://988lifeline.org/. TEXAS — A troubling new study is putting a spotlight on a growing mental health crisis among children and teens.

Local NewsOctober is Mental Health Awareness MonthOctober is Mental Health Awareness Month—and this Saturday is World Mental Health Day. More than 1 in 5 American adults experience mental illness every single year -- that’s more than 60 million people. 1 in 4 of those people say they cannot get the help they need. On average, people wait 11 years from their first symptoms before they ever receive treatment. One of the biggest factors in mental health is something much simpler than most people realize: Connection. Belonging. Community.1 in 6 people worldwide struggle with loneliness. And research shows that isolation makes mental health significantly worse. That is where Crossroads Clubhouse in Warren comes in. Part of Macomb County Community Mental Health, Crossroads creates a real community for adults with severe and persistent mental illness. A place to belong, to build skills and to do meaningful work. Jennifer Zimmerman, Crossroads’ program director, joined Local 4 Live to talk more about the program. You can watch the full interview in the video at the beginning of this article. Copyright 2026 by WDIV ClickOnDetroit - All rights reserved.

It’s that time of year again — and we’re bringing the biggest conversations in women’s health to Los Angeles! Flow Space’s annual Women’s Health Summit is happening next week, bringing together some of the leading experts and voices in women’s health for an afternoon of smart, candid conversations about what it really takes to thrive in midlife. On Thursday, October 15, we’ll take over Penske Media’s beautiful rooftop in Sawtelle for a day packed with the topics everyone is talking about: wearable health tracking, peptides and GLP-1s, psychedelics, and the complexities of managing menopause during breast cancer treatment.

Landry Kalembo in front of the McMaster University Health Sciences building in Hamilton, Ontario. Landry Kalembo’s experience of displacement is driving him to ask whose stories are captured in health research, and what happens when they aren’t.

With back-to-school routines now in full swing, it’s a great time to remember good oral health practices for the whole family. Good oral health is an important part of a child’s overall health and well-being. Healthy teeth and gums can help children eat, speak, learn and feel their best every day.

American healthcare, the priciest healthcare system in the world, is set to get even more expensiveIn the coming weeks, the roughly 160 million Americans who get health insurance through work will log into their benefits portals and pick a plan for 2027. Even for people used to rising healthcare costs, what they see may come as a shock. Employer health plan costs are projected to rise 8 to 10% next year, the largest increase in more than 20 years and double the average increase of the 2010s. This spike is just the second in a series of three successive shocks to healthcare costs and coverage. The first came in January 2026, when the 24.3 million ACA Marketplace enrollees saw their after-subsidy premiums rise by an average of 114%. The second is the sharp increase in premiums and out-of-pocket costs for those who get insurance at work, the third year in a row of elevated increases. The third comes next January, when Medicaid work-reporting requirements take effect, which CBO projects will eventually push nearly 6 million people out of coverage. History suggests that the American political system makes a bold attempt to reform healthcare about once a generation.

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Ottawa Public Health is warning that residents who visited a number of restaurants and grocery stores last week may have been exposed to the measles virus. The public health agency says it is investigating confirmed measles infections in two Ottawa residents with known exposure to measles outside Ontario. At this time, OPH says, risk to the general population remains low. The announcement contains a list of eight locations with corresponding dates and times where people may have been exposed to the highly contagious respiratory infection:Tim Hortons at 3224 Hawthorne Rd. When: Thursday, Oct. 1 between 5:30 and 8 p.m. Monitor until Thursday, Oct. 22Your Independent Grocer at 1910 St. Laurent Blvd. When: Friday, Oct. 2 between 3:15 and 5:45 p.m. Monitor until Friday, Oct. 23Rexall Drugstore at 1910 St. Laurent Blvd. When: Friday, Oct. 2 between 3:45 and 6 p.m. Monitor until Friday, Oct. 23Metro Supermarket at 2261 Walkley Rd. When: Friday, Oct. 2 between 4 and 6:15 p.m. Monitor until Friday, Oct. 23Subway at 3190 Hawthorne Rd. When: Friday, Oct. 2 between 5:30 and 8 p.m. Monitor until Friday, Oct. 23McDonald's at 1796 St. Laurent Blvd. When: Friday, Oct. 2 between 5:30 and 8:00 p.m.