Southeastern Manitoba men's mental health group uses ATVs as therapy tools - CBC

Frost advisories are popping up all over Ontario after a stormy weather event and a hot summer. A tumbling ridge of high pressure is clearing the sky and easing the winds across the province. This will help usher in cooler temperatures going into the overnight. The ridge will create conditions for patchy frost to appear, especially in low-lying and frost-prone areas. Environment and Climate Change Canada (ECCC) has issued widespread frost advisories in the Nickel Belt, cottage country, and even parts of southeastern Ontario. RELATED: El Niño has put Canada's weather on pauseEnsure you take preventative measures to protect cold sensitive plants. These frosty conditions will create overnight lows in the low to mid-single digits in cottage country and southeastern Ontario. Content continues belowThe frost risk is expected to lessen going into Saturday night, thanks to a system moving towards the southwest that will bump up temperatures. WATCH: The '3 Cs' that mean frost could be on deckStay with The Weather Network for more updates on Ontario’s weather

A common liver disease affecting nearly 30% of adults worldwide is far more complex than previously understood. Researchers at Mayo Clinic have identified five biologically distinct forms of the condition, each associated with different risks of serious health complications, including heart disease, liver failure, cancer, and the need for a liver transplant. The findings, published in Nature Communications, come from a collaboration between Mayo Clinic and Virginia Tech. Scientists discovered that metabolic dysfunction-associated steatotic liver disease, or MASLD, can develop through several different biological pathways. Some are closely connected to obesity and diabetes, while others appear to be driven by inherited genetic differences.

IntroductionHypertension is a major global health concern and a leading cause of morbidity and mortality [1]. It is estimated that more than 19 million annual deaths are attributed to cardiovascular disease (CVD) worldwide [2]. In Japan, high blood pressure (BP) has been consistently identified as a strong risk factor for the national burden of CVD, in terms of notable incidence, mortality, direct/indirect healthcare costs, and quality-adjusted life years (QALYs) associated with this condition [3, 4]. Although age-specific mean BP declined in Japan over recent decades [5], hypertension remains a critical public health issue, particularly because of the rapid aging population. The proportion of individuals aged ≥65 years is projected to reach approximately 35% by 2040 in Japan [6], highlighting a potentially higher future burden of hypertension in this country. While the prevalence of hypertension increases with age, population aging may offset the benefits of declining BP levels in each age group. As a result, the future burden of hypertension in Japan remains uncertain.

It also established a $2.5m professorship to support its cardiothoracic surgery leadership. The National Heart Centre Singapore (NHCS) has launched a centre to develop cardiovascular disease models using heart cells derived from Asian patients. The Centre for Integrative Human Cell Research and Translation (CIPHER), launched on 16 October, uses blood samples from Asian patients to grow heart muscle cells for disease research and drug testing. It is the first centre in Singapore dedicated to cardiovascular research using this approach. NHCS also announced the establishment of the Tong Ming Chuan Professorship in Cardiothoracic Surgery, the first professorship in the field under the SingHealth Duke-NUS Academic Medical Centre (AMC). CIPHER aims to address gaps in cardiovascular research, as some heart conditions develop earlier and present differently in Asian populations than in Western populations. Many treatments have historically been developed using models that do not fully reflect Asian biology. The centre uses blood samples to generate induced pluripotent stem cells, which are developed into heart muscle cells carrying features of each patient’s disease.