PRIMA at 3 years: Early surgical risk, durable vision gains in GA - Ophthalmology Times
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Ehsan Rahimy, MD, says most PRIMA serious adverse events occurred early, while vision gains held through 36 months. Patients with geographic atrophy (GA) have had treatments that slow lesion growth but nothing that restores central vision once it is lost. That changed in July 2026, when Science Corporation received a CE mark for the PRIMA photovoltaic retinal implant, making it commercially available across 30 European countries. The US Food and Drug Administration (FDA) review is ongoing. The 12-month results of the pivotal PRIMAvera trial were published in the New England Journal of Medicine in October 2025. In that trial, 26 of 32 participants who reached 12 months (81.3%) had a clinically meaningful gain in prosthetic visual acuity. The same report recorded 26 serious adverse events (SAEs) in 19 participants, most occurring within the first 2 months after implantation. As retina specialists begin fielding patient questions about the device, longer-term safety data and clear patient-selection criteria have become the central questions. At the American Academy of Ophthalmology 2026 Annual Meeting, Ehsan Rahimy, MD, presented 36-month safety data from PRIMAvera.
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