Marlene Ginader's Canadian Psycho premieres at the Firehall Arts Centre, March 31 to April 12 - Stir

image: Psycho-cardiovascular interaction network (PCIN): from mind to heart via multilevel mechanisms. The psycho-cardiovascular interaction network (PCIN) links psychological and psychiatric conditions with cardiovascular health and disease through bidirectional associations. System-level mechanisms include hypothalamic–pituitary–adrenal (HPA) axis and autonomic nervous system (ANS) imbalance, chronic inflammation, platelet activation, unhealthy behaviors, and sleep/circadian disruption. These converge on key signaling pathways: brain-derived neurotrophic factor (BDNF), prokineticin/prokineticin receptor (PROK/PKR), mitogen-activated protein kinase (MAPK), 5-hydroxytryptamine/5-HT2A receptor (5-HT/5-HT2A-R), and NOD-like receptor protein 3 (NLRP3). A new review proposes the psycho-cardiovascular interaction network (PCIN), a framework that links psychological and psychiatric factors with cardiovascular health and disease. The review integrates epidemiological evidence, system-level mechanisms, and molecular signaling pathways to explain how depression, anxiety, chronic stress, and other mental health conditions may contribute to cardiovascular disease (CVD), and vice versa.

A a man died of a freak accident on the property on Friday during a walking tour.

'The fair is proceeding as planned and final preparations are underway,' a spokesperson said. The post After Protests and Riots, Art Basel Readies Paris Show appeared first on Artnet News .