Help shape health and wellness planning for Urban and Away-from-Home First Nations - First Nations Health Authority

Overview of real-world treatment patterns and clinical outcomes with [¹⁷⁷Lu]Lu-PSMA-617 in patients with metastatic castration-resistant prostate cancer treated within the French Early-Access Program. The figure summarizes patient population, treatment exposure, efficacy outcomes and safety findings from routine clinical practice. Credit: KPL, Paris. Prostate-specific membrane antigen (PSMA)-targeted radiopharmaceutical therapy is safe and effective for patients with metastatic castration-resistant prostate cancer (mCRPC) in routine clinical practice, consistent with outcomes from the VISION trial. An analysis of outcomes from a French early-access program, the largest real-world cohort of patients studied to date, confirms the benefit-risk profile of the therapy, while also shedding light on patient selection and use trends. This research was published in The Journal of Nuclear Medicine.

Kim Chi, MD, FRCPC, discusses the rationale and design of the phase 3 KLK2-comPAS trial evaluating pasritamig alone and in combination with JNJ-9401 in patients with mCRPC. In this video, Kim Chi, MD, FRCP, discusses the rationale and design of the phase 3 KLK2-comPAS trial (NCT07164443) evaluating pasritamig, alone and in combination with JNJ-9401, in patients with metastatic castration-resistant prostate cancer (mCRPC) who have exhausted available life-prolonging treatment options. The design of the study was presented at the 2026 European Society for Medical Oncology Annual Congress in Madrid, Spain as a trials in progress poster. Chi is a medical oncologist at BC Cancer in Vancouver, Canada, and a professor of medicine at the University of British Columbia. According to Chi, the KLK2-comPAS trial builds on the potential of kallikrein-related peptidase 2 (KLK2) as a therapeutic target because of its expression in normal and malignant prostate tissue. Pasritamig is a bispecific antibody that engages CD3 on T cells and KLK2 on prostate cancer cells to stimulate a targeted immune response.

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More people are low in iron than in any other micronutrient, according to the American Society of Hematology. But many live with fatigue, weakness, brain fog and other symptoms for months or years before a deficiency is caught. Nearly one-third of adults in the United States may be iron deficient, according to a 2024 study. And routine screening among children and pregnant women — who are at high risk — may miss more than 70 per cent of cases. Researchers estimate approximately 10.5 per cent of Canadians are iron deficient. Read more here. Some people online are self-diagnosing, citing dark under-eye circles and pale skin as evidence that they are low in iron. Social media influencers call the look “ferritin face,” named after a protein that stores the element in the body. Iron deficiency is common, prevalent and underrecognized, said Dr. Ariela Marshall, associate professor of medicine at the University of Minnesota. New diagnostic recommendations, which ASH released in September, aim to ensure more patients secure early treatment.

Our editors handpick the products that we feature. We may earn commission from the links on this page. World-renowned neuroscientist Wendy Suzuki, PhD, is no stranger to the brain—or to what makes it tick. In fact, when she stopped by the Oprah Daily offices to speak with our editorial director, Pilar Guzmán, for our In Conversation With series, Dr. Suzuki brought a preserved human brain along with her, which made for a particularly fascinating episode. The NYU professor, dean of the College of Art & Sciences, and bestselling author of Good Anxiety and Healthy Brain, Happy Life joined Guzmán to discuss all things brain health, particularly when it comes to the seismic hormonal shifts (like pregnancy, menopause) that so many women go through. She also talked to us about what first drew her to studying the mind (spoiler: It always comes down to a great professor); the neuroscience behind anxiety and what it’s trying to tell you; and, of course, the best ways to boost your brain health. Watch the full video of their conversation above. Now 44% OffSofia Lodato (she/her) is a staff writer at Oprah Daily.

LondonA Western University-led research initiative to develop a cure for HIV has received $24 million in federal funding. Goal is to create a potential HIV cure suitable for 1st clinical trials in humansJessica Singer · CBC News · Posted: Oct 23, 2026 11:18 AM EDT | Last Updated: 2 hours agoListen to this articleEstimated 1 minuteThe audio version of this article is generated by AI-based technology. Mispronunciations can occur. We are working with our partners to continually review and improve the results. Professor Eric Arts is the executive director of the Impackt Facility and the Canada Research Chair in HIV Pathogenesis and Viral Control. (Western University)A Western University-led research initiative to develop a cure for HIV has received $24 million in federal funds. The international project, called IMMUNEQUITY, is expected to deliver clinical trials for HIV treatments that will be tested in humans for the first time in Canada and Uganda, according to a Friday news release from Western University.