Unusual Selenium-Containing Protein Reduces Sulfur Compounds in Bacteria - Technology Networks

Sustainable packaging is only the beginning. What a medicine is made from—and how its ingredients are produced—matters just as much. Yet the synthesis of compounds for pharmaceutical research can still depend on fossil feedstocks, high temperatures, strong oxidants and metals that raise costs and complicate purification. Two recently published studies from Colmenares' group at IPC PAS demonstrate that cleaner chemistry can begin at the level of a single chemical bond. The studies are published in the journal Ultrasonics Sonochemistry and Chemistry—A European Journal.

Curcumin, berberine, and several other plant-derived substances have drawn attention from scientists because of their potential anti-inflammatory and anticancer effects. New research from Wroclaw Medical University and the University of Wroclaw suggests, however, that these compounds can behave very differently. A substance that appears powerful against cancer cells may not necessarily have the best safety profile. The researchers examined five compounds: curcumin, berberine, biochanin A, cucurbitacin E, and CAPE (caffeic acid phenethyl ester), a component of propolis. They compared how each one affected fibrosarcoma cells and healthy muscle cells.