Pomegranate Compound Improves Heart Function Up to 80% in Mice With Heart Failure - ScienceAlert
Each time you eat a juicy pomegranate, your gut bacteria can produce a natural metabolite called urolithin A. This little-known compound is making a big splash. In recent years, scientists have paid close attention to urolithin A because it seems to have anti-inflammatory, antioxidant, anti-tumor, and anti-aging properties. Initial evidence in humans even suggests that urolithin A can help the body remove aged or damaged parts of our cells, thereby improving their overall health. Now, for the first time, researchers at King's College London (KCL) have found evidence that urolithin A can activate a protein that plays a key role in heart health. In mouse models with stiff and failing hearts, urolithin A improved measures of heart function by as much as 80 percent compared to untreated animals, according to a press release from KCL. The findings are published in Science Advances, with financial support from the British Heart Foundation. The results have scientists hopeful that urolithin A could be a previously unidentified treatment option for a common form of heart failure.
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