Permeability heterogeneity controls fluid migration and microseismicity evolution in The Geysers geothermal field, California - Nature

IntroductionClimate change is resulting in an increasing frequency of heatwaves, which leads to a substantial increase in deaths and hospitalizations in the summer1. Besides heat, cold continues to be a major health threat and accounts for substantial proportions of deaths2 and hospitalizations3,4. Current evidence suggests heat to be associated with more hospitalizations due to infectious diseases, respiratory, cardiovascular, and neurological outcomes5,6,7, while cold temperatures were primarily associated with cardiovascular and respiratory conditions8. Compared to mortality, hospitalizations reflect a more sensitive indicator of temperature-related health effects, including also less severe cases. Moreover, temperature-related (emergency) hospitalizations are of central public health importance since they naturally reflect unplanned admissions, reveal vulnerabilities in the population, and thus represent a source of uncertainty and potential strain on existing hospital capacity.

IntroductionProstate cancer is the most common malignancy in men that accounts for 10% of male cancer-related deaths and is expected to increase in incidence in the coming decades1. Its clinical trajectory is highly variable, with disease courses ranging from localised disease with long indolent phases that often require no therapy, to early-onset cancer that typically necessitates definitive treatment with curative intent2 and life-threatening metastatic prostate cancer3. The management of newly diagnosed prostate cancer is primarily based on established clinical and pathological information along with small gene or mRNA panels. The most pressing unmet clinical needs include reliable prognostic approaches to minimize overtreatment and the identification of therapeutic targets4. This is especially challenging due to the considerable molecular heterogeneity of the disease. Its genomic landscape is dominated by structural variation (SV) and copy-number alteration (CNA) drivers, while in contrast, drivers involving small mutations including single-nucleotide variants (SNVs) and insertions-deletions (indels) are relatively infrequent5,6.

Milky Way’s first microblazar candidate sits 12,000 light-years away, offering a rare ground-level lab for studying relativistic jetsA black hole 12,000 light-years away is firing a jet of plasma almost directly toward Earth. At that distance, no known or expected danger to Earth has been identified by the researchers or the institutions involved. What astronomers have actually found is rarer and more interesting than a threat. Researchers have identified IRAS 18293-0941 as a compelling candidate for the Milky Way’s first microblazar, a class of object that gives astrophysicists a close-up laboratory for studying some of the most violent physics in the galaxy. What Astronomers FoundThe discovery centers on a binary system whose black hole expels plasma jets at close to three-quarters the speed of light, pointed almost directly toward Earth. The system pairs a hot, massive star with a black hole that completes a full orbit roughly every 11.38 days. Material drawn from the companion star feeds the black hole, and some of that matter gets expelled outward as opposing jets traveling at approximately three-quarters the speed of light. Terminology matters here.

Forests that stood on Mozambique's coast thousands of years ago now lie beneath shallow seas, and they have become fish-filled "peat reefs" with marine life comparable to coral reefs, researchers report in Scientific Reports. A team from the Bazaruto Center for Scientific Studies (BCSS) Ocean Observatory, led by Mario Lebrato, documented the submerged peat in the Bazaruto Archipelago in the Western Indian Ocean. BCSS, founded in 2017, describes itself as Africa's first permanent ocean observatory. Working with universities and institutions in the U. K., U. S. and Canada, the team believes it has carried out the first ecological study of peat reefs anywhere in the tropics. Old forests, new seafloorRadiocarbon dating shows the peat formed between about 300 and 5,000 years ago, and chemical analysis indicates it came mostly from coastal land plants and trees. Some samples contain up to 40% organic carbon by dry weight. Lebrato said the coastline has very little natural hard seabed, mostly shifting sand. As rising seas expose the old peat layers, they create rare solid habitat where marine life can settle, hide and feed.

Coral bleaching restoration at Stanford – by Dan Griffin / GG Films (via SWNS, cropped) Coral bleaching has been reversed at record speed using a new method developed at Stanford University.