Nonviral delivery of chemically modified tRNA rescues nonsense mutations in cystic fibrosis - Science | AAAS

Many scientists have argued that microplastics pose a real, if often subtle, threat to human health. A study out this week may provide a vital clue as to how this harm is happening. Researchers at Columbia University and others took a close look at how microplastics behave in water. They found that when plastic is broken up into tiny fragments and surrounded by water, it can easily produce highly reactive molecules. Though more study is still needed to understand the exact health impacts of microplastics, the team’s work undercuts the assumption that plastic is always chemically passive, the authors say. “Our findings challenge the prevailing paradigm of plastic inertness [and] identify a possibly overlooked mechanism for the detrimental effects of microplastics on health and the environment,” they wrote in their paper, published Wednesday in the journal Nature. Not so inert Microplastics are any piece of plastic smaller than 5 millimeters. Over the years, scientists have increasingly raised the alarm about the likely dangers of microplastics for both people and other animals.