Integrating multi-omics technologies to decipher microbiome functions - Nature

image: On the left, GACNEs are unevenly distributed across the genome, forming distinct hotspots. On the right, the Manhattan plots highlight these clustered regions and their associations with genes involved in the Wnt signaling pathway. At the bottom, functional enrichment analysis shows the biological functions associated with genes near GACNE hotspots. Gliding has evolved independently six times in living mammals, making it a classic example of convergent evolution. Why does nature repeatedly produce similar complex adaptive traits? When distantly related species evolve similar features, do they rely on the same genetic changes, or can different genetic changes lead to similar outcomes?