Her family kept getting cancer. At 33, a saliva test explained why. - Business Insider
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Michelle York, 43, was diagnosed with Lynch syndrome 10 years ago. Lynch syndrome heightens her risk of developing multiple cancers, especially colon cancer.
On her mom's side, Michelle York has a long family history of cancer. Her great-grandmother died from colon cancer. Her grandfather had stomach and brain cancer, and his sisters died from liver, ovarian, and breast cancer, respectively. Her mother's cousin died from pancreatic cancer. Then, when York was 33, her mother came across a possible explanation: Lynch syndrome. An inherited genetic mutation, Lynch syndrome is underdiagnosed, symptomless, and increases the risk of cancers, including colorectal, uterine, stomach, ovarian, pancreatic, among others. With colon cancer in particular, it can increase lifetime risk as high as 80%, and is sometimes associated with more aggressive forms of the cancer. About 1 in 300 Americans is estimated to have Lynch syndrome, though many don't find out until after they've been diagnosed with cancer. York's mother, who was a nurse at the time and had read about Lynch through her work, decided to get tested.
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