Vancouver-based foot health entrepreneurs appearing on 'Dragons' Den' this week - Vancouver Is Awesome

The Den Family Social⁠(opens in a new window) is a Denver-based social club that brings together hospitality, community, work, and play to give parents a place where they can feel like themselves and their children are welcome too. The business grew from founder Chandler Lipe’s own transition into parenthood and her belief that parents deserve elevated, inspiring spaces built with their wellbeing in mind. As The Den began construction and pre-opening for a second location, Chandler turned to ChatGPT Work to help manage the increasing administrative load. Her small team now saves 10-15 hours a week and prepares licensing and grant applications in hours instead of days, giving them more capacity to grow while staying focused on the families they serve. “ChatGPT Work allows us to build the company we need before we have the size or resources of that company.”—Chandler Lipe, Founder and CEO, The DenTurning scattered information into an action planTo open their second location, The Den’s team had to operationalize their knowledge and context from the first.

Bioengineer.org news storyFor people living with HIV, modern antiretroviral therapy can suppress the virus to levels below what standard laboratory tests can detect. Yet some patients on long-term treatment experience a curious phenomenon: a single test result showing a small, transient amount of virus in the blood, followed by an immediate return to undetectable levels. These events, known as viral blips, have puzzled clinicians and researchers for years, raising questions about whether they represent harmless statistical noise, brief bursts of viral production from hidden reservoirs, or early warnings of impending treatment failure. A new nationwide Swedish study, published in BMC Infectious Diseases, offers one of the most comprehensive answers to date. Drawing on the Swedish national InfCareHIV cohort, researchers analyzed data from 4,210 treatment-naïve adults who began antiretroviral therapy from 1 January 2007 onward, with follow-up data extracted through 30 September 2020. The median observation time was 5.5 years, with some individuals followed for as long as 13.7 years.

European Medical Journal news storyPeople living with HIV may experience subtle changes in heart muscle function even when conventional measures of cardiac performance remain normal, according to findings from a systematic review and meta-analysis. Researchers identified significantly impaired global longitudinal strain (GLS) among people with HIV compared with HIV-uninfected individuals, despite preserved left ventricular ejection fraction (LVEF) in both groups. The findings suggest that speckle-tracking echocardiography (STE) could provide additional information about early myocardial dysfunction in this population. Read the full news story here.