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New drug reverses severe fatty liver disease by repairing the gut - Science Daily

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Source: Science Daily
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An experimental drug developed at Michigan Medicine has reversed a serious form of fatty liver disease in animal studies by targeting an unexpected source of liver damage: the gut.

The compound, known as DT-109, works by reducing harmful gut bacteria, protecting the intestinal lining, and preventing inflammatory substances from reaching the liver. According to findings published in The Journal of Clinical Investigation, this approach successfully reversed metabolic dysfunction-associated steatohepatitis (MASH) in animal models, offering a promising new strategy for treating a disease that remains difficult to manage.

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