DNA From a Human Brain Gene Has Turned Up In a Virus - ScienceAlert
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Unrelated virus. (Heather Davies/SPL/Getty Images)
Some pieces of our DNA can copy themselves into new locations. Copies derived from one gene active in human brain cells appear to have taken that journey further: into a virus. Researchers found two such sequences, derived from a gene called BC200, inside molluscum contagiosum virus, which infects our skin and causes small, raised lesions. The discovery reveals an unusual genetic double life. BC200 acquired a cellular role millions of years ago, yet retained the ability to produce copies that insert themselves elsewhere. A study published in Science suggests this movement has continued throughout primate evolution, contributed to differences among human genomes, and carried BC200-derived sequences across the boundary between humans and a virus. But the virus didn't simply take a gene from a brain cell, and nothing suggests it gained anything resembling brain function. What these sequences actually do inside the virus is still unknown. BC200 works differently from most genes: it skips the step of coding for a protein altogether, producing a short RNA molecule instead – one that's especially abundant in neurons.
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