Claude discovers a novel enzyme system with CRISPR-like repeats - Anthropic

Researchers co-led by Cedars-Sinai Health Sciences University have identified an enzyme that may help protect the liver from the damage that can occur as the most common form of liver disease becomes more severe. The findings, from a preclinical study published in Nature Metabolism, could eventually support new strategies for preventing serious liver injury and progression toward liver failure. An estimated 100 million people in the U. S. have metabolic dysfunction-associated steatotic liver disease (MASLD), formerly called nonalcoholic fatty liver disease, according to the American Liver Foundation. Roughly 20% to 25% of those affected go on to develop metabolic dysfunction-associated steatohepatitis (MASH), a more serious form of the condition in which excess liver fat is accompanied by inflammation, cell injury and scarring.

Original story from Cornell University (NY, USA). A new engineered gene editing system, proven in bacteria and with promise for use in plants, animals and humans, addresses some of the limitations of current gene editing tools with the hope of improving their applications for research, for better crops or to treat diseases.